Bowenoid in situ carcinoma (BISC, Bowen’s disease) is a pre-cancerous or early cancerous skin lesion in cat that resembles squamous cell carcinoma in situ, often associated with feline papillomavirus infection.

It appears as multiple pigmented, crusty, or ulcerated lesions, typically on the head, neck, or limbs of older cats.

Cause: linked to feline papillomavirus.

Appearance: Pigmented plaques, crusts, or nodules; may resemble warts or scabs.

Diagnosis: Biopsy & histopathology are essential to confirm BISC.

Progression: Can remain in situ (non-invasive) or may develop into invasive squamous cell carcinoma if not treated.

Laser surgery is one of the preferred treatments for Bowenoid in situ carcinoma due to its precision & reduced trauma to surrounding tissues.

Benefits of Laser Surgery:

Precision: Targets lesions with minimal impact on surrounding healthy tissue

Reduced bleeding:
Lasers seals blood vessels

Faster healing:
Less inflammation & tissue damage

Repeatable:
Lesions can recur & laser treatment can be repeated with minimal cumulative damage

Considerations:
General anesthesia is required.
Recurrence is common, especially if the underlying viral infection persists.
Follow-up monitoring is crucial to detect new or recurrent lesions early.

Other Treatment Options:

Cryotherapy (freezing lesions)

Topical immune modulators (e.g., imiquimod, though use in cats is cautious & off-label)

Surgical excision

Photodynamic therapy

Monitoring & Prevention:

Regular skin checks, especially in sun-exposed or light-skinned cats.

Consider reducing sun exposure (keep indoors during peak UV hours).

Summary:

Laser surgery is an effective & often recommended option for treating Bowenoid in situ carcinoma in cats, particularly when the lesions are numerous or located in cosmetically or functionally sensitive areas. However, recurrence is common, & long-term management may involve multiple treatments & close veterinary follow-up.